# 114 Photoredox-catalyzed tandem difluoromethylation/cyclization of 1-acryloyl-2-arylbenzimidazole for the synthesis of
发布时间：2024-10-18 15:25:00
Photoredox-catalyzed tandem difluoromethylation/cyclization of 1-acryloyl-2-arylbenzimidazole for the synthesis of difluoromethylated benzo[4,5]imidazo[2,1-a]isoquinolin-6(5H)-one derivatives
Jinwei Yuan,a,*Hongzhao Qu,a Wenfeng Jia,a Jinling Li,b,* Liangru Yang,a Yongmei Xiao,a Lingbo Quc
The article was first published on 08 Oct 2024
Org. Biomol. Chem., 2024, Advance Article
https://doi.org/10.1039/D4OB01413H
A simple and convenient visible-light-promoted radical cascade difluoromethylation/cyclization reaction to access various difluoromethylated benzo[4,5]imidazo[2,1-a]isoquinolin-6(5H)-ones was developed using difluoromethyltriphenylphosphonium bromide salt as a difluoromethylated reagent under mild conditions.
Jinwei Yuan,a,*Hongzhao Qu,a Wenfeng Jia,a Jinling Li,b,* Liangru Yang,a Yongmei Xiao,a Lingbo Quc
The article was first published on 08 Oct 2024
Org. Biomol. Chem., 2024, Advance Article
https://doi.org/10.1039/D4OB01413H
A simple and convenient visible-light-promoted radical cascade difluoromethylation/cyclization reaction to access various difluoromethylated benzo[4,5]imidazo[2,1-a]isoquinolin-6(5H)-ones was developed using difluoromethyltriphenylphosphonium bromide salt as a difluoromethylated reagent under mild conditions.