# 105 Selectfluor-Mediated Tandem Cyclization of Enaminones with diselenides toward the synthesis of 3-Selenylated Chrom
发布时间：2024-01-11 12:18:30
Selectfluor-Mediated Tandem Cyclization of Enaminones with diselenides toward the synthesis of 3-Selenylated Chromones
Ji-Hong Xia,a Qian Chen,b Jin-Wei Yuan,b,*Wei-Shuo Shi,b Liang-Ru Yang,b,* Yong-Mei Xiaob
RSC Adv., 2023,13, 26948-26959
https://doi.org/10.1039/D3RA05246J
A practical and metal-free approach for the regioselective selenation of chromones employing Selectfluor reagent under mild conditions is described. The developed method is suitable for a wide substrate scope and affords 3-selenylated chromones in good to excellent yield with high selectivity. An ionic mechanism is proposed for this transformation. Furthermore, the application of potassium thiocyanate with enaminones for the synthesis of thiocyano chromones in this transformation is also successful.